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SNUPN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNUPN Antibody (Center) AP16617c
    SNUPN Antibody (Center) (Cat. #AP16617c) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SNUPN antibody detected the SNUPN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95149
Other Accession NP_001036046.1, NP_005692.1, NP_001036053.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41143 Da
Antigen Region 200-228 aa
Additional Information
Gene ID 10073
Other Names Snurportin-1, RNA U transporter 1, SNUPN, RNUT1, SPN1
Target/Specificity This SNUPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human SNUPN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNUPN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RNUT1, SPN1
Function Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Cellular Location Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta. It is re- exported to the cytoplasm by the XPO1-dependent nuclear export receptor pathway
Citations (0)

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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.


Goette, M., et al. Biophys. J. 97(2):581-589(2009)
Monecke, T., et al. Science 324(5930):1087-1091(2009)
Ospina, J.K., et al. Mol. Biol. Cell 16(10):4660-4671(2005)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Strasser, A., et al. EMBO J. 24(13):2235-2243(2005)

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$ 295.00
$ 99.00
Cat# AP16617c
(40 western blots)
Availability: In Stock
Bulk Size
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