FAIM Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9NVQ4 |
Other Accession | NP_001028202.1, NP_001028203.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 20215 Da |
Antigen Region | 65-93 aa |
Gene ID | 55179 |
---|---|
Other Names | Fas apoptotic inhibitory molecule 1, FAIM, FAIM1 |
Target/Specificity | This FAIM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the Central region of human FAIM. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FAIM Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FAIM |
---|---|
Synonyms | FAIM1 |
Function | Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
FAIM plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells (By similarity).
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Li, G., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 8), 935-937 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kaku, H., et al. J. Immunol. 183(3):1667-1674(2009)
Segura, M.F., et al. J. Neurosci. 27(42):11228-11241(2007)
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