PTPRCAP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q14761 |
Other Accession | NP_005599.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 21196 Da |
Antigen Region | 90-118 aa |
Gene ID | 5790 |
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Other Names | Protein tyrosine phosphatase receptor type C-associated protein, PTPRC-associated protein, CD45-associated protein, CD45-AP, Lymphocyte phosphatase-associated phosphoprotein, PTPRCAP, LPAP |
Target/Specificity | This PTPRCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human PTPRCAP. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PTPRCAP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PTPRCAP |
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Synonyms | LPAP |
Cellular Location | Membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein.
References
Ju, H., et al. Neoplasia 11(12):1340-1347(2009)
Cocco, E., et al. J. Neurol. 251(9):1085-1088(2004)
Vogel, A., et al. Genes Immun. 4(1):79-81(2003)
Kirchgessner, H., et al. J. Exp. Med. 193(11):1269-1284(2001)
Woods, M.L., et al. EMBO J. 20(6):1232-1244(2001)
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