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STAG1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - STAG1 Antibody (Center) AP16638C
    STAG1 Antibody (Center) (Cat. #AP16638c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the STAG1 antibody detected the STAG1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WVM7
Other Accession Q9D3E6, NP_005853.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 144427 Da
Antigen Region 540-568 aa
Additional Information
Gene ID 10274
Other Names Cohesin subunit SA-1, SCC3 homolog 1, Stromal antigen 1, STAG1, SA1
Target/Specificity This STAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-568 amino acids from the Central region of human STAG1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTAG1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAG1
Synonyms SA1
Function Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
Cellular Location Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of cohesin is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation
Research Areas
Citations (0)

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This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.


Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009) :
Canudas, S., et al. J. Cell Biol. 187(2):165-173(2009)
Rubio, E.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(24):8309-8314(2008)
Watrin, E., et al. Curr. Biol. 16(9):863-874(2006)
Losada, A., et al. J. Cell. Sci. 118 (PT 10), 2133-2141 (2005) :

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$ 295.00
$ 99.00
Cat# AP16638C
(40 western blots)
Availability: In Stock
Bulk Size
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