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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLA2G12A Antibody (Center)   

PLA2G12A Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PLA2G12A Antibody (Center) AP16639c
    PLA2G12A Antibody (Center) (Cat. #AP16639c) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PLA2G12A antibody detected the PLA2G12A protein (arrow).
  • WB - PLA2G12A Antibody (Center) AP16639c
    Western blot analysis of PLA2G12A (arrow) using rabbit polyclonal PLA2G12A Antibody (Center) (Cat. #AP16639c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLA2G12A gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BZM1
Other Accession NP_110448.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21067 Da
Antigen Region 55-83 aa
Additional Information
Gene ID 81579
Other Names Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A, PLA2G12A, PLA2G12
Target/Specificity This PLA2G12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human PLA2G12A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLA2G12A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G12A
Synonyms PLA2G12
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine.
Cellular Location Secreted. Cytoplasm
Tissue Location Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas
Research Areas
Citations (0)

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Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7401-7406(2010)
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 295.00
$ 99.00
Cat# AP16639c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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