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RNF103 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16642c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16642c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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- Backgrounds
RNF103 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | O00237 |
| Other Accession | Q9EPZ8, Q9R1W3, NP_005658.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 79405 Da |
RNF103 Antibody (Center) - Additional info | |
| Gene ID 7844 | |
| Other Names RNF103; ZFP103; E3 ubiquitin-protein ligase RNF103; KF-1; RING finger protein 103; Zinc finger protein 103 homolog | |
| Target/Specificity This RNF103 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RNF103. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RNF103 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RNF103 Antibody (Center) - Protein Information | |
| Name RNF103 | |
| Synonyms ZFP103 | |
| Function Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway | |
| Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein | |
| Tissue Location Highly expressed in the normal cerebellum but not in the cerebral cortex | |
RNF103 Antibody (Center) - Related products
AP16642c: RNF103 Antibody (Center)
RI14562: RNF103 predesign siRNA
RNF103 Antibody (Center) - Application data
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RNF103 Antibody (Center) (Cat. #AP16642c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the RNF103 antibody detected the RNF103 protein (arrow).
RNF103 Antibody (Center) - Research Areas
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BACKGROUND
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream VPS24 (vacuolar protein sorting 24 homolog) gene. [provided by RefSeq].
REFERENCES
Scheper, J., et al. Proteins 74(1):92-103(2009) Maruyama, Y., et al. Biochem. Biophys. Res. Commun. 374(4):737-741(2008) Yang, Y., et al. Meth. Enzymol. 398, 103-112 (2005) : Nishioka, G., et al. J Neural Transm 110(3):277-285(2003) Yamada, M., et al. Biochem. Biophys. Res. Commun. 278(1):150-157(2000)
