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RBAK Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RBAK Antibody (N-term) AP16643a
    RBAK Antibody (N-term) (Cat. #AP16643a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RBAK antibody detected the RBAK protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NYW8
Other Accession NP_066986.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 82995 Da
Antigen Region 74-102 aa
Additional Information
Gene ID 57786
Other Names RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, hRBaK, Zinc finger protein 769, RBAK, ZNF769
Target/Specificity This RBAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human RBAK.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRBAK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBAK
Synonyms ZNF769
Function May repress E2F-dependent transcription. May promote AR- dependent transcription.
Cellular Location Nucleus.
Tissue Location Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
Citations (0)
citation

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Background

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.

References

Trynka, G., et al. Gut 58(8):1078-1083(2009)
Ma, Y., et al. BMC Genomics 10, 109 (2009) :
Jeske, Y.W., et al. Clin. Exp. Pharmacol. Physiol. 35(4):380-385(2008)
So, A., et al. Clin. Endocrinol. (Oxf) 65(6):829-831(2006)
Vertegaal, A.C., et al. Mol. Cell Proteomics 5(12):2298-2310(2006)

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$ 182.50
$ 70.00
Cat# AP16643a
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