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DCTD Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DCTD Antibody (N-term) AP16651A
    DCTD Antibody (N-term) (Cat. #AP16651a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DCTD antibody detected the DCTD protein (arrow).
  • WB - DCTD Antibody (N-term) AP16651A
    Western blot analysis of DCTD (arrow) using rabbit polyclonal DCTD Antibody (N-term) (Cat. #AP16651a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DCTD gene.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P32321
Other Accession Q5M9G0, Q8K2D6, NP_001912.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20016 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 1635
Other Names Deoxycytidylate deaminase, dCMP deaminase, DCTD
Target/Specificity This DCTD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCTD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCTD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCTD
Function Supplies the nucleotide substrate for thymidylate synthetase.
Citations (0)

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Background

The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.

References

Tanaka, M., et al. Cancer (2010) In press :
Okazaki, T., et al. Clin. Cancer Res. 16(1):320-329(2010)
Rha, S.Y., et al. Oncologist 12(6):622-630(2007)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)

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$ 295.00
$ 99.00
Cat# AP16651A
Size:
Quantity:
(40 western blots)
Availability: In Stock
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