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ZNF263 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ZNF263 Antibody (Center) AP16655c
    ZNF263 Antibody (Center) (Cat. #AP16655c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the ZNF263 antibody detected the ZNF263 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O14978
Other Accession NP_005732.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 77299 Da
Antigen Region 318-346 aa
Additional Information
Gene ID 10127
Other Names Zinc finger protein 263, Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12, ZNF263, FPM315, ZKSCAN12
Target/Specificity This ZNF263 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the Central region of human ZNF263.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZNF263 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF263 (HGNC:13056)
Function Transcription factor that binds to the consensus sequence 5'- TCCTCCC-3' and acts as a transcriptional repressor (PubMed:32051553). Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (PubMed:32051553). Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (PubMed:32277030).
Cellular Location Nucleus.
Tissue Location Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte
Citations (0)
citation

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Background

ZNF263 might play an important role in basic cellular processes as a transcriptional repressor.

References

Frietze, S., et al. J. Biol. Chem. 285(2):1393-1403(2010)
Martin, J., et al. Nature 432(7020):988-994(2004)
Yokoyama, M., et al. Biochim. Biophys. Acta 1353(1):13-17(1997)
Okubo, K., et al. Genomics 30(2):178-186(1995)

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$ 365.00
$ 140.00
Cat# AP16655c
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