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IRX5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IRX5 Antibody (C-term) AP16657b
    IRX5 Antibody (C-term) (Cat. #AP16657b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the IRX5 antibody detected the IRX5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78411
Other Accession Q9JKQ4, NP_005844.4
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50361 Da
Antigen Region 455-483 aa
Additional Information
Gene ID 10265
Other Names Iroquois-class homeodomain protein IRX-5, Homeodomain protein IRX-2A, Homeodomain protein IRXB2, Iroquois homeobox protein 5, IRX5, IRX2A, IRXB2
Target/Specificity This IRX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-483 amino acids from the C-terminal region of human IRX5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIRX5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRX5
Synonyms IRX2A, IRXB2
Function Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
Cellular Location Nucleus.
Research Areas
Citations (0)

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IRX5 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.


Myrthue, A., et al. Clin. Cancer Res. 14(11):3562-3570(2008)
Bruneau, B.G. Med Sci (Paris) 22(3):231-232(2006)
Ogura, K., et al. Cytogenet. Cell Genet. 92 (3-4), 320-325 (2001) :
Lewis, M.T., et al. Cell Tissue Res. 296(3):549-554(1999)

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Cat# AP16657b
(40 western blots)
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