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ST8SIA6 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ST8SIA6 Antibody (Center) AP16680C
    ST8SIA6 Antibody (Center) (Cat. #AP16680c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ST8SIA6 antibody detected the ST8SIA6 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P61647
Other Accession NP_001004470.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44836 Da
Antigen Region 138-167 aa
Additional Information
Gene ID 338596
Other Names Alpha-2, 8-sialyltransferase 8F, 2499-, Sialyltransferase 8F, SIAT8-F, Sialyltransferase St8Sia VI, ST8SiaVI, ST8SIA6, SIAT8F
Target/Specificity This ST8SIA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human ST8SIA6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsST8SIA6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ST8SIA6
Synonyms SIAT8F
Function Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc- alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups (By similarity).
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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Background

Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).

References

Yang, J.J., et al. JAMA 301(4):393-403(2009)
Avril, T., et al. J. Leukoc. Biol. 80(4):787-796(2006)
Harduin-Lepers, A., et al. Glycobiology 15(8):805-817(2005)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Takashima, S., et al. J. Biol. Chem. 277(27):24030-24038(2002)

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$ 295.00
$ 99.00
Cat# AP16680C
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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