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PANX3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96QZ0 |
| Other Accession | NP_443191.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44683 Da |
| Antigen Region | 3-31 aa |
| Gene ID | 116337 |
|---|---|
| Other Names | Pannexin-3, PANX3 |
| Target/Specificity | This PANX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human PANX3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PANX3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PANX3 (HGNC:20573) |
|---|---|
| Function | Regulator of osteoblast differentiation by functionning as a Ca(2+) channel in the endoplasmic reticulum which regulates calmodulin (CaM) pathways. Allows ATP release into the extracellular space and activation or purinergic receptors. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351} Cell junction, gap junction {ECO:0000250|UniProtKB:Q8CEG0}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the innexin family. Innexin family members are known to be the structural components of gap junctions.
References
Iwamoto, T., et al. J. Biol. Chem. 285(24):18948-18958(2010)
Bhalla-Gehi, R., et al. J. Biol. Chem. 285(12):9147-9160(2010)
Penuela, S., et al. J. Cell. Sci. 120 (PT 21), 3772-3783 (2007) :
Baranova, A., et al. Genomics 83(4):706-716(2004)
Bruzzone, R., et al. Proc. Natl. Acad. Sci. U.S.A. 100(23):13644-13649(2003)
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