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ZBTB38 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZBTB38 Antibody (N-term) AP16697A
    ZBTB38 Antibody (N-term) (Cat. #AP16697a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the ZBTB38 antibody detected the ZBTB38 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NAP3
Other Accession NP_001073881.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 134257 Da
Antigen Region 133-161 aa
Additional Information
Gene ID 253461
Other Names Zinc finger and BTB domain-containing protein 38, ZBTB38 (HGNC:26636)
Target/Specificity This ZBTB38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of human ZBTB38.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZBTB38 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB38 (HGNC:26636)
Function Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl- CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA- replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters.
Citations (0)

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The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types.


Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Cho, Y.S., et al. Nat. Genet. 41(5):527-534(2009)
Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :

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Cat# AP16697A
(40 western blots)
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