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HECW2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HECW2 Antibody (Center) AP16705c
    HECW2 Antibody (Center) (Cat. #AP16705c) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the HECW2 antibody detected the HECW2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2P5
Other Accession Q6I6G8, NP_065811.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 175769 Da
Antigen Region 848-876 aa
Additional Information
Gene ID 57520
Other Names E3 ubiquitin-protein ligase HECW2, 632-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2
Target/Specificity This HECW2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 848-876 amino acids from the Central region of human HECW2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHECW2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HECW2
Synonyms KIAA1301, NEDL2
Function E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
Cellular Location Cytoplasm.
Tissue Location Predominantly expressed in adult brain, lung and heart.
Research Areas
Citations (0)

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E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Miyazaki, K., et al. Biochem. Biophys. Res. Commun. 308(1):106-113(2003)

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Cat# AP16705c
(40 western blots)
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