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ZNF541 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9H0D2 |
| Other Accession | Q4R2Z8, NP_001094889.1 |
| Reactivity | Human |
| Predicted | Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 145587 Da |
| Antigen Region | 737-765 aa |
| Gene ID | 84215 |
|---|---|
| Other Names | Zinc finger protein 541, ZNF541 |
| Target/Specificity | This ZNF541 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the Central region of human ZNF541. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZNF541 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZNF541 |
|---|---|
| Function | Transcription regulator which is essential for male fertility and for the completion of meiotic prophase in spermatocytes. Regulates progression of the pachytene stage of meiotic prophase by activating the expression of genes involved in meiosis during spermatogenesis. Maintains the repression of pre-pachytene transcriptional programs, including meiotic double-strand breaks (DSB) formation genes in pachytene spermatocytes and suppresses aberrant DSB formation after mid-pachytene, thus ensuring meiosis progression. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q0GGX2, ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE- ProRule:PRU00624} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis (By similarity).
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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