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TGFBI Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TGFBI Antibody (N-term) AP16708a
    Western blot analysis of TGFBI (arrow) using rabbit polyclonal TGFBI Antibody (N-term) (Cat. #AP16708a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TGFBI gene.
  • FC - TGFBI Antibody (N-term) AP16708a
    TGFBI Antibody (N-term) (Cat. #AP16708a) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15582
Other Accession Q95215, O11780, P82198, NP_000349.1
Reactivity Human
Predicted Mouse, Pig, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 74681 Da
Antigen Region 106-135 aa
Additional Information
Gene ID 7045
Other Names Transforming growth factor-beta-induced protein ig-h3, Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, TGFBI, BIGH3
Target/Specificity This TGFBI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human TGFBI.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTGFBI Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BIGH3
Function Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.
Cellular Location Secreted, extracellular space, extracellular matrix. Note=May be associated both with microfibrils and with the cell surface
Tissue Location Highly expressed in the corneal epithelium.
Research Areas
Citations (0)

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This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Edelstein, S.L., et al. Cornea 29(6):698-700(2010)
Romero, P., et al. Mol. Vis. 16, 1601-1609 (2010) :
Paliwal, P., et al. Mol. Vis. 16, 1429-1438 (2010) :
Yang, J., et al. Mol. Vis. 16, 1186-1193 (2010) :

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$ 295.00
$ 99.00
Cat# AP16708a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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