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CPT1B Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CPT1B Antibody (C-term) AP16713B
    CPT1B Antibody (C-term) (Cat. #AP16713b) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CPT1B antibody detected the CPT1B protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q92523
Other Accession NP_001138609.1, NP_001138607.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 87801 Da
Antigen Region 744-770 aa
Additional Information
Gene ID 1375
Other Names Carnitine O-palmitoyltransferase 1, muscle isoform, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, CPTI-M, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, CPT1B, KIAA1670
Target/Specificity This CPT1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-770 amino acids from the C-terminal region of human CPT1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCPT1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1B
Synonyms KIAA1670
Function Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion.
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein
Tissue Location Strong expression in heart and skeletal muscle. No expression in liver and kidney
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

References

Matsuo, T., et al. Biochem. Genet. 48 (3-4), 193-201 (2010) :
Miljkovic, I., et al. Obesity (Silver Spring) 17(7):1396-1401(2009)
Miyagawa, T., et al. PLoS ONE 4 (4), E5394 (2009) :
van der Leij, F.R., et al. J. Biol. Chem. 277(30):26994-27005(2002)
Yamazaki, N., et al. J. Biol. Chem. 275(41):31739-31746(2000)

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$ 182.50
$ 70.00
Cat# AP16713B
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