|Application ||WB, E|
|Calculated MW||60011 Da|
|Antigen Region||176-204 aa|
|Other Names||Zinc finger protein 350, KRAB zinc finger protein ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein ZBRK1, ZNF350, ZBRK1|
|Target/Specificity||This ZNF350 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the Central region of human ZNF350.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF350 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.|
|Cellular Location||Nucleus. Nucleus matrix. Note=Associated with the nuclear matrix|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF350 is a transcriptional repressor. It binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
Liao, C.C., et al. J. Biol. Chem. 285(43):33134-33143(2010)
Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Yarden, R.I., et al. Mol. Carcinog. 49(6):545-555(2010)
Rajaraman, P., et al. Neuro-oncology 12(1):37-48(2010)
Groner, A.C., et al. PLoS Genet. 6 (3), E1000869 (2010) :
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