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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLCN2 Antibody (N-term)   

CLCN2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLCN2 Antibody (N-term) AP16730a
    CLCN2 Antibody (N-term) (Cat. #AP16730a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow).
  • WB - CLCN2 Antibody (N-term) AP16730a
    CLCN2 Antibody (N-term) (Cat. #AP16730a) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51788
Other Accession P35525, P51789, NP_001164559.1
Reactivity Human, Mouse
Predicted Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 98535 Da
Antigen Region 209-237 aa
Additional Information
Gene ID 1181
Other Names Chloride channel protein 2, ClC-2, CLCN2
Target/Specificity This CLCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human CLCN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLCN2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLCN2
Function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells
Research Areas
Citations (0)

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The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.


Scheper, G.C., et al. Genet Test Mol Biomarkers 14(2):255-257(2010)
Cornejo, I., et al. J. Cell. Physiol. 221(3):650-657(2009)
Thompson, C.H., et al. J. Biol. Chem. 284(38):26051-26062(2009)
Kleefuss-Lie, A., et al. Nat. Genet. 41(9):954-955(2009)
Klaus, F., et al. Biochem. Biophys. Res. Commun. 381(3):407-411(2009)

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$ 295.00
$ 99.00
Cat# AP16730a
(40 western blots)
Availability: In Stock
Bulk Size
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