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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARHGEF6 Antibody (C-term)   

ARHGEF6 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARHGEF6 Antibody (C-term) AP16738b
    ARHGEF6 Antibody (C-term) (Cat. #AP16738b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARHGEF6 antibody detected the ARHGEF6 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15052
Other Accession NP_004831.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 87499 Da
Antigen Region 614-641 aa
Additional Information
Gene ID 9459
Other Names Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
Target/Specificity This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARHGEF6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms COOL2, KIAA0006, PIXA
Function Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Cellular Location Cell projection, lamellipodium
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].


Maiti, A.K. Pharmacogenomics J. 10(2):94-104(2010)
Eriguchi, M., et al. J. Neurol. Sci. 290 (1-2), 80-85 (2010) :
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Lim, J.W., et al. Scand. J. Gastroenterol. 44(10):1166-1172(2009)
Baek, H.Y., et al. Ann. N. Y. Acad. Sci. 1096, 18-23 (2007) :

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$ 295.00
$ 99.00
Cat# AP16738b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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