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CSDE1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75534 |
| Other Accession | NP_001123995.1, NP_001007554.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 88885 Da |
| Antigen Region | 588-615 aa |
| Gene ID | 7812 |
|---|---|
| Other Names | Cold shock domain-containing protein E1, N-ras upstream gene protein, Protein UNR, CSDE1, D1S155E, KIAA0885, NRU, UNR |
| Target/Specificity | This CSDE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-615 amino acids from the C-terminal region of human CSDE1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CSDE1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CSDE1 (HGNC:29905) |
|---|---|
| Function | RNA-binding protein involved in translationally coupled mRNA turnover (PubMed:11051545, PubMed:15314026). Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (PubMed:11051545, PubMed:15314026). Required for efficient formation of stress granules (PubMed:29395067). |
| Cellular Location | Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body |
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Provided below are standard protocols that you may find useful for product applications.
Background
CSDE1 is a RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Anderson, E.C., et al. J. Gen. Virol. 88 (PT 11), 3043-3052 (2007) :
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
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