UBXN8 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O00124 |
Other Accession | Q2TBH5, NP_005662.1 |
Reactivity | Human |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 30541 Da |
Antigen Region | 59-87 aa |
Gene ID | 7993 |
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Other Names | UBX domain-containing protein 8, Reproduction 8 protein, Rep-8 protein, UBX domain-containing protein 6, UBXN8, D8S2298E, REP8, UBXD6 |
Target/Specificity | This UBXN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human UBXN8. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | UBXN8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UBXN8 |
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Synonyms | D8S2298E, REP8, UBXD6 |
Function | Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Expressed abundantly in ovary and testis, and weakly in all other tissues tested |
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Provided below are standard protocols that you may find useful for product applications.
Background
UBXN8 may play a role in reproduction.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Yamabe, Y., et al. Genomics 39(2):198-204(1997)
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