|Application ||WB, E|
|Calculated MW||176799 Da|
|Antigen Region||1503-1530 aa|
|Other Names||Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIM, ARHGEF5, TIM|
|Target/Specificity||This ARHGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1503-1530 amino acids from the C-terminal region of human ARHGEF5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARHGEF5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Mainly expressed in kidney, liver, pancreas, lung and placenta|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wang, Z., et al. J. Biol. Chem. 284(42):28599-28606(2009)
Lin, Y.M., et al. Mol. Carcinog. 47(12):925-933(2008)
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
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