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OR1D2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OR1D2 Antibody (C-term) AP16747b
    OR1D2 Antibody (C-term) (Cat. #AP16747b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the OR1D2 antibody detected the OR1D2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P34982
Other Accession NP_002539.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35240 Da
Antigen Region 286-312 aa
Additional Information
Gene ID 4991
Other Names Olfactory receptor 1D2, Olfactory receptor 17-4, OR17-4, Olfactory receptor OR17-6, Olfactory receptor-like protein HGMP07E, OR1D2, OLFR1
Target/Specificity This OR1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human OR1D2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOR1D2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OR1D2
Synonyms OLFR1
Function Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.
Cellular Location Cell membrane; Multi-pass membrane protein. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal
Tissue Location Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium
Research Areas
Citations (0)
citation

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Background

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

References

Neuhaus, E.M., et al. J. Cell. Sci. 119 (PT 15), 3047-3056 (2006) :
Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)
Spehr, M., et al. Science 299(5615):2054-2058(2003)
Fuchs, T., et al. Genomics 80(3):295-302(2002)
Glusman, G., et al. Genomics 63(2):227-245(2000)

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$ 365.00
$ 140.00
Cat# AP16747b
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