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RCN1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15293 |
| Other Accession | Q05186, NP_002892.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38890 Da |
| Antigen Region | 305-331 aa |
| Gene ID | 5954 |
|---|---|
| Other Names | Reticulocalbin-1, RCN1, RCN |
| Target/Specificity | This RCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human RCN1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RCN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RCN1 |
|---|---|
| Synonyms | RCN |
| Function | May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. |
| Cellular Location | Endoplasmic reticulum lumen. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
References
Favor, J., et al. Genetics 182(4):1077-1088(2009)
Hansen, G.A., et al. Mol. Cell. Biochem. 320 (1-2), 25-33 (2009) :
Cooper, C.R., et al. J. Cell. Biochem. 104(6):2298-2309(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
Taylor, T.D., et al. Nature 440(7083):497-500(2006)
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