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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KRT3 Antibody (Center)   

KRT3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KRT3 Antibody (Center) AP16759c
    KRT3 Antibody (Center) (Cat. #AP16759c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KRT3 antibody detected the KRT3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12035
Other Accession NP_476429.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64417 Da
Antigen Region 414-441 aa
Additional Information
Gene ID 3850
Other Names Keratin, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, CK-3, Keratin-3, K3, Type-II keratin Kb3, KRT3
Target/Specificity This KRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKRT3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT3
Tissue Location Cornea specific.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.


Szaflik, J.P., et al. Mol. Vis. 14, 1713-1718 (2008) :
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Chen, Y.T., et al. Cornea 24(8):928-932(2005)
Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)
Irvine, A.D., et al. Nat. Genet. 16(2):184-187(1997)

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Cat# AP16759c
(40 western blots)
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