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RFX1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16766b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16766b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
RFX1 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P22670 |
| Other Accession | P48377, NP_002909.4 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 104758 Da |
RFX1 Antibody (C-term) - Additional info | |
| Gene ID 5989 | |
| Other Names RFX1; MHC class II regulatory factor RFX1; Enhancer factor C; Regulatory factor X 1; Transcription factor RFX1 | |
| Target/Specificity This RFX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 895-925 amino acids from the C-terminal region of human RFX1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RFX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RFX1 Antibody (C-term) - Protein Information | |
| Name RFX1 | |
| Function Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter | |
| Cellular Location Nucleus. | |
RFX1 Antibody (C-term) - Related products
RFX1 Antibody (C-term) - Application data
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RFX1 Antibody (C-term) (Cat. #AP16766b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the RFX1 antibody detected the RFX1 protein (arrow).
RFX1 Antibody (C-term) - Research Areas
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BACKGROUND
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.
REFERENCES
Zhao, M., et al. J. Autoimmun. 35(1):58-69(2010) Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) : Hsu, Y.C., et al. J. Biol. Chem. 285(18):13885-13895(2010) Seguin-Estevez, Q., et al. J. Immunol. 183(4):2545-2553(2009) Zhang, Y., et al. Mol. Biol. (Mosk.) 43(1):77-84(2009)
