|Application ||WB, E|
|Other Accession||NP_001132928.1, NP_777619.1|
|Calculated MW||53991 Da|
|Antigen Region||241-269 aa|
|Other Names||Putative transporter SVOPL, SV2-related protein-like, SVOP-like protein, SVOPL|
|Target/Specificity||This SVOPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human SVOPL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SVOPL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
SVOPL (putative transporter SVOPL), also known as SV2-related protein-like, is a 492 amino acid multi-pass membrane protein belonging to the major facilitator superfamily. SVOPL is a paralog to synaptic vesicle protein (SVOP) that exists as two alternatively spliced isoforms. The gene encoding SVOPL maps to human chromosome 7q34. Chromosome 7 is approximately 158 milllion bases long, encodes over 1,000 genes and makes up approximately 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Deletions of portions of the q arm of chromosome 7 are linked to myeloid disorders, including acute myelogenous leukemia and myelodysplasia.
Jacobsson, J.A., et al. Genomics 90(5):595-609(2007)
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