Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   C18orf26 Antibody (N-term)   

C18orf26 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - C18orf26 Antibody (N-term) AP16785a
    C18orf26 Antibody (N-term) (Cat. #AP16785a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the C18orf26 antibody detected the C18orf26 protein (arrow).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N1N2
Other Accession NP_775900.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 6-34 aa
Additional Information
Other Names Dynactin-associated protein, Full, DYNAP, C18orf26
Target/Specificity This C18orf26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human C18orf26.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC18orf26 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DYNAP
Synonyms C18orf26
Function Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'.
Cellular Location Golgi apparatus membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note=Concentrated at cell-cell borders. Localizes at membranes in a microtubule-dependent manner
Tissue Location Expressed in fibroblast and numerous cancer cell lines (at protein level). EMBL; AK096425; BAC04784.1; -; mRNA EMBL; AC091135; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS11957.1; - RefSeq; NP_775900.1; NM_173629.2 UniGene; Hs.376146; - ProteinModelPortal; Q8N1N2; - STRING; 9606.ENSP00000315265; - PhosphoSitePlus; Q8N1N2; - BioMuta; DYNAP; - DMDM; 73620598; - PaxDb; Q8N1N2; - PRIDE; Q8N1N2; - Ensembl; ENST00000321600; ENSP00000315265; ENSG00000178690 GeneID; 284254; - KEGG; hsa:284254; - UCSC; uc002lfq.1; human CTD; 284254; - GeneCards; DYNAP; - HGNC; HGNC:26808; DYNAP HPA; HPA011148; - neXtProt; NX_Q8N1N2; - OpenTargets; ENSG00000178690; - PharmGKB; PA134946407; - eggNOG; ENOG410J4ES; Eukaryota eggNOG; ENOG4111DTF; LUCA GeneTree; ENSGT00400000022381; - HOGENOM; HOG000111950; - InParanoid; Q8N1N2; - OMA; NDQEAHS; - OrthoDB; EOG091G0NYO; - PhylomeDB; Q8N1N2; - TreeFam; TF338599; - BioCyc; ZFISH:ENSG00000178690-MONOMER; - GenomeRNAi; 284254; - PRO; PR:Q8N1N2; - Proteomes; UP000005640; Chromosome 18 Bgee; ENSG00000178690; - CleanEx; HS_C18orf26; - ExpressionAtlas; Q8N1N2; baseline and differential GO; GO:0005794; C:Golgi apparatus; IDA:UniProtKB GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0005886; C:plasma membrane; IDA:UniProtKB GO; GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB GO; GO:1901625; P:cellular response to ergosterol; IDA:UniProtKB GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB InterPro; IPR031379; CLLAC Pfam; PF15675; CLLAC; 1 1: Evidence at protein level; Cell membrane; Complete proteome; Golgi apparatus; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix CHAIN 1 210 Dynactin-associated protein /FTId=PRO_0000079315 TOPO_DOM 1 113 Cytoplasmic. TRANSMEM 114 134 Helical; Signal-anchor for type II membrane protein. TOPO_DOM 135 210 Extracellular. COMPBIAS 172 207 Thr-rich VARIANT 38 38 V -> A (in dbSNP:rs35428499) /FTId=VAR_033751 VARIANT 189 189 T -> P (in dbSNP:rs9947055) /FTId=VAR_033752 SEQUENCE 210 AA; 22529 MW; E94FE6D340D3CF79 CRC64; MVADIKGNEQ IEKYSWREAC DTGSSRMDRK HGKYILNVEH SENQPPITHP NDQEAHSSIC WCLPSNDITS DVSPNLTGVC VNPGILAHSR CLQSESCNTQ VKEYCRNDWS MWKVFLACLL ACVIMTAIGV LIICLVNNKG SANSSIVIQL STNDGECVTV KPGTPSPACP PTMTTTSTVP ASTATESTTS TATAATTSTE PITVAPTDHL
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

C18orf26 (chromosome 18 open reading frame 26) is a 210 amino acid single pass membrane protein that is encoded by a gene which maps to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million nucleotide bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

References

Kunoh, T., et al. Mol. Cancer Ther. 9(11):2934-2942(2010)

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 295.00
$ 99.00
Cat# AP16785a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown-Flash18
Terms & Conditions