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SIT1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SIT1 Antibody (C-term) AP16787b
    SIT1 Antibody (C-term) (Cat. #AP16787b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SIT1 antibody detected the SIT1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y3P8
Other Accession Q5M869, NP_055265.1
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21126 Da
Antigen Region 161-189 aa
Additional Information
Gene ID 27240
Other Names Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT
Target/Specificity This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSIT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIT1
Synonyms SIT
Function Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells. Involved in positive selection of T-cells.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma
Research Areas
Citations (0)

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Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.


Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Tedoldi, S., et al. Blood 107(1):213-221(2006)
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)

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$ 295.00
$ 99.00
Cat# AP16787b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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