|Application ||WB, E|
|Other Accession||Q9WUC8, Q922V4, Q2KID6, NP_002660.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||57194 Da|
|Antigen Region||17-45 aa|
|Other Names||Pleiotropic regulator 1, PLRG1|
|Target/Specificity||This PLRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human PLRG1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PLRG1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.|
|Cellular Location||Nucleus. Nucleus speckle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
PLRG1 is necessary for spliceosome assembly and for pre-mRNA splicing.
Lleres, D., et al. EMBO Rep. 11(6):445-451(2010)
Dehghan, A., et al. Circ Cardiovasc Genet 2(2):125-133(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Ajuh, P., et al. Nucleic Acids Res. 31(21):6104-6116(2003)
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