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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MARCKSL1 Antibody (C-term)   

MARCKSL1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MARCKSL1 Antibody (C-term) AP16792b
    MARCKSL1 Antibody (C-term) (Cat. #AP16792b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MARCKSL1 antibody detected the MARCKSL1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49006
Other Accession Q9EPH2, P35566, P28667, Q0VBZ9, NP_075385.1
Reactivity Human
Predicted Bovine, Mouse, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 19529 Da
Antigen Region 132-160 aa
Additional Information
Gene ID 65108
Other Names MARCKS-related protein, MARCKS-like protein 1, Macrophage myristoylated alanine-rich C kinase substrate, Mac-MARCKS, MacMARCKS, MARCKSL1, MLP, MRP
Target/Specificity This MARCKSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the C-terminal region of human MARCKSL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMARCKSL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MLP, MRP
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).
Cellular Location Cytoplasm. Cell membrane. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity) In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity).
Research Areas
Citations (0)

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MARCKSL1 may be involved in coupling the protein kinase C and calmodulin signal transduction systems.


Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Jordanova, A., et al. Nat. Genet. 38(2):197-202(2006)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)

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$ 295.00
$ 99.00
Cat# AP16792b
(40 western blots)
Availability: In Stock
Bulk Size
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