|Application ||WB, E|
|Other Accession||Q792S6, O35425, NP_115904.1|
|Calculated MW||23280 Da|
|Antigen Region||1-30 aa|
|Other Names||Bcl-2-related ovarian killer protein, hBOK, Bcl-2-like protein 9, Bcl2-L-9, BOK, BCL2L9|
|Target/Specificity||This BOK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BOK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BOK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis in a manner dependent on BAX and BAK.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=The transmembrane domain is necessary and sufficient for Golgi and ER targeting|
|Tissue Location||Expressed in brain, liver, appendix and lymphoid tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary.
Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)
Ray, J.E., et al. Cell Death Differ. 17(5):846-859(2010)
Zhang, H., et al. Int. J. Oncol. 34(4):1135-1138(2009)
Rodriguez, J.M., et al. J. Biol. Chem. 281(32):22729-22735(2006)
Bartholomeusz, G., et al. Mol. Carcinog. 45(2):73-83(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.