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SHBG Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SHBG Antibody (N-term) AP16796a
    SHBG Antibody (N-term) (Cat. #AP16796a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHBG antibody detected the SHBG protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04278
Other Accession NP_001031.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43779 Da
Antigen Region 69-96 aa
Additional Information
Gene ID 6462
Other Names Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP, Testosterone-estradiol-binding globulin, TeBG, Testosterone-estrogen-binding globulin, SHBG
Target/Specificity This SHBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the N-terminal region of human SHBG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSHBG Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Cellular Location Secreted. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis
Tissue Location Isoform 1 and isoform 2 are present in liver and testis
Research Areas
Citations (0)

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This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.


Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Xita, N., et al. Exp. Clin. Endocrinol. Diabetes (2010) In press :
Diaz, M., et al. Fertil. Steril. (2010) In press :
Hatzi, E., et al. Gynecol. Endocrinol. (2010) In press :
Iwasaki, M., et al. Nutr Cancer 62(4):466-475(2010)

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$ 295.00
$ 99.00
Cat# AP16796a
(40 western blots)
Availability: In Stock
Bulk Size
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