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KRT75 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KRT75 Antibody (N-term) AP16811A
    KRT75 Antibody (N-term) (Cat. #AP16811a) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the KRT75 antibody detected the KRT75 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95678
Other Accession NP_004684.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59560 Da
Antigen Region 66-92 aa
Additional Information
Gene ID 9119
Other Names Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, hK6hf, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18, KRT75, K6HF, KB18
Target/Specificity This KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the N-terminal region of human KRT75.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKRT75 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT75
Synonyms K6HF, KB18
Function Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle.
Tissue Location Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).
Research Areas
Citations (0)

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This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).


Sperling, L.C., et al. J. Cutan. Pathol. 37(2):243-248(2010)
Liu, Z.B., et al. Tumori 95(1):53-62(2009)
Nofech-Mozes, S., et al. Int. J. Surg. Pathol. 16(4):399-406(2008)
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Roh, C., et al. Physiol. Genomics 19(2):207-217(2004)

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$ 295.00
$ 99.00
Cat# AP16811A
(40 western blots)
Availability: In Stock
Bulk Size
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