|Application ||WB, E|
|Other Accession||Q5XI28, Q9CW46, NP_597709.2|
|Calculated MW||63877 Da|
|Antigen Region||56-83 aa|
|Other Names||Ribonucleoprotein PTB-binding 1, Protein raver-1, RAVER1, KIAA1978|
|Target/Specificity||This RAVER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human RAVER1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAVER1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=Nuclear, in perinucleolar structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts. Associated with myotubes during muscle differentiation (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
RAVER1 cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lee, J.H., et al. Structure 17(6):833-842(2009)
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