|Application ||WB, E|
|Calculated MW||45534 Da|
|Antigen Region||279-308 aa|
|Other Names||Lipase member N, 311-, Lipase-like abhydrolase domain-containing protein 4, LIPN, LIPL4|
|Target/Specificity||This LIPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human LIPN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LIPN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.|
|Tissue Location||Highly expressed in the epidermis in the granular keratinocytes. Also detected in other tissues, although at much lower levels, including lung and spleen|
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LIPN plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.
Toulza, E., et al. Genome Biol. 8 (6), R107 (2007) :
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