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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SEPT8 Antibody (C-term)   

SEPT8 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPT8 Antibody (C-term) AP16836b
    SEPT8 Antibody (C-term) (Cat. #AP16836b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEPT8 antibody detected the SEPT8 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92599
Other Accession NP_001092281.1, NP_001092282.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55756 Da
Antigen Region 407-436 aa
Additional Information
Gene ID 23176
Other Names Septin-8, SEPT8, KIAA0202
Target/Specificity This SEPT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-436 amino acids from the C-terminal region of human SEPT8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPT8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT8
Synonyms KIAA0202
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
Tissue Location Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary
Research Areas
Citations (0)

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SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking (Blaser et al., 2003 [PubMed 12909369]).


Souza, T.A., et al. Protein J. 29(5):328-335(2010)
Ridruechai, C., et al. Genes Immun. 11(5):416-422(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Xin, X., et al. J. Histochem. Cytochem. 55(11):1089-1094(2007)
Steels, J.D., et al. Cell Motil. Cytoskeleton 64(10):794-807(2007)

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$ 295.00
$ 99.00
Cat# AP16836b
(40 western blots)
Availability: In Stock
Bulk Size
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