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SEPT11 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPT11 Antibody (Center) AP16837c
    SEPT11 Antibody (Center) (Cat. #AP16837c) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SEPT11 antibody detected the SEPT11 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NVA2
Other Accession B3GNI6, Q8C1B7, Q4R555, A2VE99, NP_060713.1
Reactivity Human
Predicted Bovine, Monkey, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49398 Da
Antigen Region 353-382 aa
Additional Information
Gene ID 55752
Other Names Septin-11, SEPT11
Target/Specificity This SEPT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the Central region of human SEPT11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPT11 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT11
Function Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
Cellular Location Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria
Tissue Location Widely expressed, except in leukocytes.
Research Areas
Citations (0)

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SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Huang, G.L., et al. World J. Gastroenterol. 16(16):2046-2054(2010)
Mostowy, S., et al. J. Biol. Chem. 284(17):11613-11621(2009)
Ding, X., et al. Mol. Cells 25(3):385-389(2008)
Xin, X., et al. J. Histochem. Cytochem. 55(11):1089-1094(2007)

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$ 295.00
$ 99.00
Cat# AP16837c
(40 western blots)
Availability: In Stock
Bulk Size
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