|Application ||WB, E|
|Other Accession||Q68FU8, Q8CH02, NP_757386.2|
|Calculated MW||72471 Da|
|Antigen Region||364-393 aa|
|Other Names||SURP and G-patch domain-containing protein 1, RNA-binding protein RBP, Splicing factor 4, SUGP1, SF4|
|Target/Specificity||This SF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the Central region of human SF4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SF4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in pre-mRNA splicing.|
|Tissue Location||Detected in adult testis and heart, and in adult and fetal brain, kidney and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
SF4 is a member of the SURP family of splicing factors.
Hegele, R.A., et al. Hum. Mol. Genet. 18(21):4189-4194(2009)
Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Sampson, N.D., et al. Gene 305(1):91-100(2003)
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