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TRPC7 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HCX4 |
| Other Accession | NP_065122.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 99562 Da |
| Antigen Region | 834-862 aa |
| Gene ID | 57113 |
|---|---|
| Other Names | Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7 |
| Target/Specificity | This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRPC7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRPC7 |
|---|---|
| Synonyms | TRP7 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Nucleus envelope |
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Provided below are standard protocols that you may find useful for product applications.
Background
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Miyagi, K., et al. J. Biol. Chem. 284(49):34400-34412(2009)
Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) :
Abed, E., et al. Cell Prolif. 40(6):849-865(2007)
Numaga, T., et al. Handb Exp Pharmacol 179, 143-151 (2007) :
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