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MCRS1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MCRS1 Antibody (N-term) AP16872A
    MCRS1 Antibody (N-term) (Cat. #AP16872a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCRS1 antibody detected the MCRS1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96EZ8
Other Accession Q99L90, NP_006328.2, NP_001012300.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51803 Da
Antigen Region 35-63 aa
Additional Information
Gene ID 10445
Other Names Microspherule protein 1, 58 kDa microspherule protein, Cell cycle-regulated factor p78, INO80 complex subunit J, MCRS2, MCRS1, INO80Q, MSP58
Target/Specificity This MCRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human MCRS1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMCRS1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MCRS1
Synonyms INO80Q, MSP58
Function Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.
Cellular Location Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus
Tissue Location Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes
Citations (0)

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MCRS1 modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. May be an inhibitor of TERT telomerase activity.


Lin, W., et al. J. Cell. Mol. Med. 13 (11-12), 4608-4622 (2009) :
Shi, H., et al. Cancer Sci. 100(9):1585-1590(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Wu, J.L., et al. BMC Cell Biol. 10, 9 (2009) :
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 295.00
$ 99.00
Cat# AP16872A
(40 western blots)
Availability: In Stock
Bulk Size
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