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RMI1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RMI1 Antibody (N-term) AP16875a
    RMI1 Antibody (N-term) (Cat. #AP16875a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RMI1 antibody detected the RMI1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H9A7
Other Accession NP_079221.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70144 Da
Antigen Region 105-133 aa
Additional Information
Gene ID 80010
Other Names RecQ-mediated genome instability protein 1, BLM-associated protein of 75 kDa, BLAP75, FAAP75, RMI1, C9orf76
Target/Specificity This RMI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the N-terminal region of human RMI1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRMI1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RMI1
Synonyms C9orf76
Function Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Cellular Location Nucleus. Note=Forms foci in response to DNA damage
Citations (0)

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RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM].


Yang, J., et al. J. Biol. Chem. 285(28):21426-21436(2010)
Frank, B., et al. Carcinogenesis 31(3):442-445(2010)
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Luedeke, M., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3030-3035(2009)
Broberg, K., et al. BMC Cancer 9, 140 (2009) :

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$ 295.00
$ 99.00
Cat# AP16875a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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