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HPS3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HPS3 Antibody (N-term) AP16879a
    HPS3 Antibody (N-term) (Cat. #AP16879a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the HPS3 antibody detected the HPS3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969F9
Other Accession NP_115759.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 113736 Da
Antigen Region 262-290 aa
Additional Information
Gene ID 84343
Other Names Hermansky-Pudlak syndrome 3 protein, HPS3
Target/Specificity This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHPS3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HPS3
Function Involved in early stages of melanosome biogenesis and maturation.
Cellular Location Cytoplasm.
Tissue Location Widely expressed. Higher levels of expression are observed in kidney, liver and placenta
Research Areas
Citations (0)

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This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq].


Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32(6):448-453(2010)
Huizing, M., et al. Platelets 18(2):150-157(2007)
Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126(1):85-90(2006)
Boissy, R.E., et al. Am. J. Pathol. 166(1):231-240(2005)
Helip-Wooley, A., et al. BMC Cell Biol. 6, 33 (2005) :

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$ 295.00
$ 99.00
Cat# AP16879a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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