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IQGAP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IQGAP1 Antibody (N-term) AP16889A
    IQGAP1 Antibody (N-term) (Cat. #AP16889a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the IQGAP1 antibody detected the IQGAP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P46940
Other Accession NP_003861.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 189252 Da
Antigen Region 256-285 aa
Additional Information
Gene ID 8826
Other Names Ras GTPase-activating-like protein IQGAP1, p195, IQGAP1, KIAA0051
Target/Specificity This IQGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the N-terminal region of human IQGAP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIQGAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0051
Function Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Cellular Location Cell membrane.
Tissue Location Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas
Research Areas
Citations (0)

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This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.


Hayashi, H., et al. Int. J. Cancer 126(11):2563-2574(2010)
Liang, S., et al. Proteomics 10(7):1474-1483(2010)
Nakhaei-Nejad, M., et al. Eur. J. Immunol. 40(1):204-213(2010)
Wang, J.B., et al. J. Cell. Sci. 122 (PT 12), 2024-2033 (2009) :
Usatyuk, P.V., et al. J. Biol. Chem. 284(22):15339-15352(2009)

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$ 295.00
$ 99.00
Cat# AP16889A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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