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NHLH1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NHLH1 Antibody (Center) AP16897c
    NHLH1 Antibody (Center) (Cat. #AP16897c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NHLH1 antibody detected the NHLH1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02575
Other Accession NP_005589.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 14618 Da
Antigen Region 38-67 aa
Additional Information
Gene ID 4807
Other Names Helix-loop-helix protein 1, HEN-1, Class A basic helix-loop-helix protein 35, bHLHa35, Nescient helix loop helix 1, NSCL-1, NHLH1, BHLHA35, HEN1
Target/Specificity This NHLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the Central region of human NHLH1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNHLH1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NHLH1
Synonyms BHLHA35, HEN1
Function May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}
Research Areas
Citations (0)

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The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM].


Manetopoulos, C., et al. Biochem. Biophys. Res. Commun. 307(4):891-899(2003)
Bao, J., et al. Development 127(2):425-435(2000)
Lipkowitz, S., et al. J. Biol. Chem. 267(29):21065-21071(1992)
Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89(18):8492-8496(1992)
Begley, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 89(1):38-42(1992)

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Cat# AP16897c
(40 western blots)
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