|Application ||WB, E|
|Calculated MW||60016 Da|
|Antigen Region||530-559 aa|
|Other Names||Chondroitin sulfate proteoglycan 5, Acidic leucine-rich EGF-like domain-containing brain protein, Neuroglycan C, CSPG5, CALEB, NGC|
|Target/Specificity||This CSPG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-559 amino acids from the C-terminal region of human CSPG5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSPG5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts.|
|Tissue Location||Restricted to brain (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
CSPG5 may function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
So, H.C., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :
Ichihara-Tanaka, K., et al. J. Biol. Chem. 281(41):30857-30864(2006)
Aono, S., et al. J. Neurosci. Res. 83(1):110-118(2006)
Kinugasa, Y., et al. Biochem. Biophys. Res. Commun. 321(4):1045-1049(2004)
Hassel, B., et al. J. Biol. Chem. 278(41):40136-40143(2003)
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