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LYZL6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75951 |
| Other Accession | NP_065159.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 16956 Da |
| Antigen Region | 37-65 aa |
| Gene ID | 57151 |
|---|---|
| Other Names | Lysozyme-like protein 6, LYZL6, LYC1 |
| Target/Specificity | This LYZL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human LYZL6. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LYZL6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LYZL6 |
|---|---|
| Synonyms | LYC1 |
| Function | May be involved sperm-egg plasma membrane adhesion and fusion during fertilization (PubMed:28182716). Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus (PubMed:28182716, PubMed:24013621). Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH (PubMed:28182716). Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6 (PubMed:28182716). |
| Cellular Location | Secreted. Cell surface. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9DA11}. Note=Detected on the postacrosomal membrane of mature spermatozoa (PubMed:28182716) |
| Tissue Location | Expressed in testis, epididymis and spermatozoa (at protein level) (PubMed:16014814, PubMed:28182716). Expressed in late- stage spermatocytes and round spermatids (PubMed:28182716) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL6 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Zhang, K., et al. Biol. Reprod. 73(5):1064-1071(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nomiyama, H., et al. J. Interferon Cytokine Res. 19(3):227-234(1999)
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