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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTP4A1 Antibody (C-term)   

PTP4A1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTP4A1 Antibody (C-term) AP16923b
    PTP4A1 Antibody (C-term) (Cat. #AP16923b) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PTP4A1 antibody detected the PTP4A1 protein (arrow).
  • WB - PTP4A1 Antibody (C-term) AP16923b
    Western blot analysis of PTP4A1 (arrow) using rabbit polyclonal PTP4A1 Antibody (C-term) (Cat. #AP16923b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTP4A1 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q93096
Other Accession Q78EG7, Q63739, Q9TSM6, NP_003454.1
Reactivity Human, Mouse
Predicted Monkey, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 19815 Da
Antigen Region 140-168 aa
Additional Information
Gene ID 7803
Other Names Protein tyrosine phosphatase type IVA 1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
Target/Specificity This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTP4A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTP4A1
Synonyms PRL1, PTPCAAX1
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
Cellular Location Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=And mitotic spindle
Tissue Location Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq].


Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Skinner, A.L., et al. Biochemistry 48(20):4262-4272(2009)
Luo, Y., et al. Biochemistry 48(8):1838-1846(2009)
Min, S.H., et al. Oncogene 28(4):545-554(2009)
Liu, Y.Q., et al. Arch. Pathol. Lab. Med. 132(8):1307-1312(2008)

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$ 295.00
$ 99.00
Cat# AP16923b
(40 western blots)
Availability: In Stock
Bulk Size
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