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TAS2R38 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P59533
Other Accession NP_789787.4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37892 Da
Antigen Region 305-332 aa
Additional Information
Gene ID 5726
Other Names Taste receptor type 2 member 38, T2R38, PTC bitter taste receptor, Taste receptor type 2 member 61, T2R61, TAS2R38, PTC
Target/Specificity This TAS2R38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-332 amino acids from the C-terminal region of human TAS2R38.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAS2R38 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAS2R38
Synonyms PTC
Function Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells
Research Areas
Citations (0)

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This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).


Reed, D.R., et al. Hum. Mol. Genet. 19(21):4278-4285(2010)
Wendell, S., et al. J. Dent. Res. 89(11):1198-1202(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wooding, S., et al. Chem. Senses 35(8):685-692(2010)
Mennella, J.A., et al. BMC Genet. 11, 60 (2010) :

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Cat# AP16929b
(40 western blots)
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